How to install the adaptyv plugin
Run both commands inside Claude Code. The first adds the marketplace once; the second installs the plugin.
/plugin marketplace add adaptyvbio/protein-design-skills
/plugin install adaptyv@protein-design-skillsWhat's inside adaptyv
24 parts read from the plugin's own files.
Skills 24
Claude loads it when the task matches- alphafold
Validate protein designs and predict complex structures using AlphaFold2 structure prediction and confidence metrics.
- bindcraft
Design protein binders using hallucination with built-in AF2 validation and joint backbone and sequence optimization.
- binder-design
Provides guidance for selecting and planning protein binder design campaigns using tools like BoltzGen, BindCraft, and RFdiffusion.
- binding-characterization
Provides guidance for planning, troubleshooting, and interpreting binding kinetics experiments using Surface Plasmon Resonance and Biolayer Interferometry.
- boltz
Predict biomolecular structures including protein complexes, protein-ligand complexes, and designed binders using open-source models.
- boltzgen
Performs all-atom protein design using a diffusion model for side-chain aware structures and ligand binding.
- campaign-manager
Orchestrates protein binder design campaigns by planning pipelines, estimating costs, and assessing design health and pass rates.
- cell-free-expression
Provides guidance for optimizing cell-free protein synthesis (CFPS) experiments, troubleshooting yields, and designing DNA templates.
- chai
Predict molecular structures including protein-protein complexes, protein-ligand complexes, and protein-DNA/RNA interactions.
- esm
Use ESM protein language models to generate embeddings, score sequences, predict complex structures, and design protein binders.
- foldseek
Perform structural homology searches and clustering using 3D protein structures against PDB and AlphaFold databases.
- germinal
Design epitope-targeted de novo antibodies and nanobodies by hallucinating CDRs on fixed frameworks.
- ipsae
Ranks protein-protein interaction designs by calculating the interprotein Score from Aligned Errors for AlphaFold and Boltz1 predictions.
- ligandmpnn
Designs protein sequences around small molecules, metal ions, cofactors, or nucleic acids to optimize binding pockets and active sites.
- mosaic
Optimizes protein binders using a JAX framework that composes multiple structure and sequence models into a single differentiable loss objective.
- pdb
Fetch, search, and analyze protein structures from the RCSB PDB database using Python or API requests.
- protein-design-workflow
Provides end-to-end guidance for protein design workflows including target preparation, backbone generation, sequence design, and structure validation.
- protein-qc
Provides quality control metrics, filtering thresholds, and composite scoring strategies for evaluating protein design quality.
- proteinmpnn
Design protein sequences using inverse folding to optimize for stability, expression, or specific backbone structures.
- protenix
Predict complex molecular structures using an open-source reproduction of AlphaFold3.
- rfdiffusion
Generate protein backbones for binder design, de novo structure generation, motif scaffolding, and symmetric oligomers using a diffusion-based model.
- setup
Configures the environment and authentication for protein design tools including biomodals and BoltzGen.
- solublempnn
Optimizes protein sequence design to improve solubility, reduce aggregation, and enhance expression yields in E. coli.
- uniprot
Retrieve protein sequences, functional annotations, domain boundaries, and PDB cross-references via the UniProt REST API.
Using adaptyv in Claude Code
Skills need no command. Claude reads them when your request matches what they describe.
Update, turn off or remove
- Update the plugin (shell)
- claude plugin update adaptyv@protein-design-skills
- Refresh the marketplace
- /plugin marketplace update protein-design-skills
- Turn it off for now
- /plugin disable adaptyv@protein-design-skills
- Remove it
- /plugin uninstall adaptyv@protein-design-skills
Skills in adaptyv
- alphafoldadaptyvbio/protein-design-skills
Validate protein designs and predict complex structures using AlphaFold2 structure prediction and confidence metrics.
2 files173stars - bindcraftadaptyvbio/protein-design-skills
Design protein binders using hallucination with built-in AF2 validation and joint backbone and sequence optimization.
3 files173stars - binder-designadaptyvbio/protein-design-skills
Provides guidance for selecting and planning protein binder design campaigns using tools like BoltzGen, BindCraft, and RFdiffusion.
2 files173stars - boltzgenadaptyvbio/protein-design-skills
Performs all-atom protein design using a diffusion model for side-chain aware structures and ligand binding.
2 files173stars - chaiadaptyvbio/protein-design-skills
Predict molecular structures including protein-protein complexes, protein-ligand complexes, and protein-DNA/RNA interactions.
2 files173stars - protein-design-workflowadaptyvbio/protein-design-skills
Provides end-to-end guidance for protein design workflows including target preparation, backbone generation, sequence design, and structure validation.
3 files173stars - protein-qcadaptyvbio/protein-design-skills
Provides quality control metrics, filtering thresholds, and composite scoring strategies for evaluating protein design quality.
5 files173stars - proteinmpnnadaptyvbio/protein-design-skills
Design protein sequences using inverse folding to optimize for stability, expression, or specific backbone structures.
2 files173stars - rfdiffusionadaptyvbio/protein-design-skills
Generate protein backbones for binder design, de novo structure generation, motif scaffolding, and symmetric oligomers using a diffusion-based model.
4 files173stars - binding-characterizationadaptyvbio/protein-design-skills
Provides guidance for planning, troubleshooting, and interpreting binding kinetics experiments using Surface Plasmon Resonance and Biolayer Interferometry.
173stars - boltzadaptyvbio/protein-design-skills
Predict biomolecular structures including protein complexes, protein-ligand complexes, and designed binders using open-source models.
173stars - campaign-manageradaptyvbio/protein-design-skills
Orchestrates protein binder design campaigns by planning pipelines, estimating costs, and assessing design health and pass rates.
173stars - cell-free-expressionadaptyvbio/protein-design-skills
Provides guidance for optimizing cell-free protein synthesis (CFPS) experiments, troubleshooting yields, and designing DNA templates.
173stars - esmadaptyvbio/protein-design-skills
Use ESM protein language models to generate embeddings, score sequences, predict complex structures, and design protein binders.
173stars - foldseekadaptyvbio/protein-design-skills
Perform structural homology searches and clustering using 3D protein structures against PDB and AlphaFold databases.
173stars - germinaladaptyvbio/protein-design-skills
Design epitope-targeted de novo antibodies and nanobodies by hallucinating CDRs on fixed frameworks.
173stars - ipsaeadaptyvbio/protein-design-skills
Ranks protein-protein interaction designs by calculating the interprotein Score from Aligned Errors for AlphaFold and Boltz1 predictions.
173stars - ligandmpnnadaptyvbio/protein-design-skills
Designs protein sequences around small molecules, metal ions, cofactors, or nucleic acids to optimize binding pockets and active sites.
173stars - mosaicadaptyvbio/protein-design-skills
Optimizes protein binders using a JAX framework that composes multiple structure and sequence models into a single differentiable loss objective.
173stars - pdbadaptyvbio/protein-design-skills
Fetch, search, and analyze protein structures from the RCSB PDB database using Python or API requests.
173stars - protenixadaptyvbio/protein-design-skills
Predict complex molecular structures using an open-source reproduction of AlphaFold3.
173stars - setupadaptyvbio/protein-design-skills
Configures the environment and authentication for protein design tools including biomodals and BoltzGen.
173stars - solublempnnadaptyvbio/protein-design-skills
Optimizes protein sequence design to improve solubility, reduce aggregation, and enhance expression yields in E. coli.
173stars - uniprotadaptyvbio/protein-design-skills
Retrieve protein sequences, functional annotations, domain boundaries, and PDB cross-references via the UniProt REST API.
173stars
adaptyv plugin questions
How do I install the adaptyv plugin?
In Claude Code run /plugin marketplace add adaptyvbio/protein-design-skills, then /plugin install adaptyv@protein-design-skills.
What does the adaptyv plugin include?
adaptyv bundles 24 skills.
How do I update or remove the adaptyv plugin?
Update it with claude plugin update adaptyv@protein-design-skills in your shell, or from the Installed tab of /plugin. Remove it with /plugin uninstall adaptyv@protein-design-skills.